SEZ6L Antibody

Code CSB-PA115417
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA115417(SEZ6L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
SEZ6L
Alternative Names
SEZ6L antibody; KIAA0927 antibody; UNQ2542/PRO6094Seizure 6-like protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human SEZ6L
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May contribute to specialized endoplasmic reticulum functions in neurons.
Gene References into Functions
  1. This is the first demonstration that genetic variants in the SEZ6L gene are associated with bipolar disorder Iin female patients and provides additional compelling evidence for genetic variation at 22q11-13 that influences BD-I risk. PMID: 22920719
  2. the addition of SEZ6L improved the performance of the Liverpool Lung Project risk model. PMID: 20424129
  3. A role of the SEZ6L Met430Ile polymorphic variant in increasing lung cancer risk. PMID: 17804757
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein Families
SEZ6 family
Tissue Specificity
Widely expressed, including adult and fetal brains and lungs. Not expressed in all lung cancer cell lines.
Database Links

HGNC: 10763

OMIM: 607021

KEGG: hsa:23544

STRING: 9606.ENSP00000248933

UniGene: Hs.194766

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