Recombinant Human Seizure 6-like protein (SEZ6L), partial

Code CSB-YP871613HU
MSDS
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Source Yeast
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Code CSB-EP871613HU
MSDS
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Source E.coli
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Code CSB-EP871613HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP871613HU
MSDS
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Source Baculovirus
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Code CSB-MP871613HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SEZ6L
Uniprot No.
Alternative Names
SEZ6L; KIAA0927; UNQ2542/PRO6094Seizure 6-like protein
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May contribute to specialized endoplasmic reticulum functions in neurons.
Gene References into Functions
  1. This is the first demonstration that genetic variants in the SEZ6L gene are associated with bipolar disorder Iin female patients and provides additional compelling evidence for genetic variation at 22q11-13 that influences BD-I risk. PMID: 22920719
  2. the addition of SEZ6L improved the performance of the Liverpool Lung Project risk model. PMID: 20424129
  3. A role of the SEZ6L Met430Ile polymorphic variant in increasing lung cancer risk. PMID: 17804757
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein Families
SEZ6 family
Tissue Specificity
Widely expressed, including adult and fetal brains and lungs. Not expressed in all lung cancer cell lines.
Database Links

HGNC: 10763

OMIM: 607021

KEGG: hsa:23544

STRING: 9606.ENSP00000248933

UniGene: Hs.194766

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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