SEZ6L2 Antibody, Biotin conjugated

Code CSB-PA761499LD01HU
Size US$166
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Product Details

Full Product Name
Seizure 6-like protein 2 anti-Homo sapiens (Human) SEZ6L2 Polyclonal antibody
Uniprot No.
Target Names
SEZ6L2
Alternative Names
SEZ6L2 antibody; PSK antibody; UNQ1903/PRO4349 antibody; Seizure 6-like protein 2 antibody
Raised in
Seizure 6-like protein 2
Species Reactivity
Human
Immunogen
Recombinant Human Seizure 6-like protein 2 protein (28-372aa)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Antigen Affinity purified & Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May contribute to specialized endoplasmic reticulum functions in neurons.
Gene References into Functions
  1. SEZ6L2 can partially correct the cathepsin D hypersecretion. PMID: 26698217
  2. These results provide an extensive ascertainment of the genetic variability of SEZ6L2 in human populations and do not support a major role for SEZ6L2 sequence variations in the susceptibility to autism spectrum disorders. PMID: 21394203
  3. significant association between autism and a coding variant in the seizure-related gene SEZ6L2 gene; SEZ6L2 expression in human fetal brain was highest in post-mitotic cortical layers, hippocampus, amygdala, and thalamus PMID: 19242545
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Detected on cell surface of lung-cancer.
Protein Families
SEZ6 family
Database Links

HGNC: 30844

OMIM: 616667

KEGG: hsa:26470

STRING: 9606.ENSP00000312550

UniGene: Hs.6314

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