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SEZ6L2 Antibody, FITC conjugated

Datasheet
Code CSB-PA761499LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SEZ6L2 Polyclonal antibody
Uniprot No.
Q6UXD5
Target Names
SEZ6L2
Alternative Names
SEZ6L2 antibody; PSK antibody; UNQ1903/PRO4349 antibody; Seizure 6-like protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Seizure 6-like protein 2 protein (28-372aa)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Antigen Affinity purified & Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May contribute to specialized endoplasmic reticulum functions in neurons.
Gene References into Functions
  1. SEZ6L2 can partially correct the cathepsin D hypersecretion. PMID: 26698217
  2. These results provide an extensive ascertainment of the genetic variability of SEZ6L2 in human populations and do not support a major role for SEZ6L2 sequence variations in the susceptibility to autism spectrum disorders. PMID: 21394203
  3. significant association between autism and a coding variant in the seizure-related gene SEZ6L2 gene; SEZ6L2 expression in human fetal brain was highest in post-mitotic cortical layers, hippocampus, amygdala, and thalamus PMID: 19242545
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Detected on cell surface of lung-cancer.
Protein Families
SEZ6 family
Database Links

HGNC: 30844

OMIM: 616667

KEGG: hsa:26470

STRING: 9606.ENSP00000312550

UniGene: Hs.6314

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