SFXN4 Antibody

Code CSB-PA253040
Size US$297
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  • Western blot analysis of extracts from HUVEC cells, using SFXN4 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SFXN4 Polyclonal antibody
Uniprot No.
Target Names
SFXN4
Alternative Names
SFXN4; BCRM1; Sideroflexin-4; Breast cancer resistance marker 1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from N-terminal of Human SFXN4.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mitochondrial amino-acid transporter. Does not act as a serine transporter: not able to mediate transport of serine into mitochondria.
Gene References into Functions
  1. Our findings establish mutations in SFXN4 as a cause of mitochondriopathy and macrocytic anemia. PMID: 24119684
  2. we isolated a cDNA encoding a novel sideroflexin protein (SFXN4), which showed 59% identity and 71% similarity to mouse sideroflexin4. PMID: 14756423
Involvement in disease
Combined oxidative phosphorylation deficiency 18 (COXPD18)
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Sideroflexin family
Database Links

HGNC: 16088

OMIM: 615564

KEGG: hsa:119559

STRING: 9606.ENSP00000347924

UniGene: Hs.655168

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