SHROOM2 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA622684LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SHROOM2 Polyclonal antibody

Uniprot No.

Q13796

Target Names

SHROOM2

Alternative Names

4832440C16 antibody; Ab2-404 antibody; Apical like protein antibody; Apical like protein APXL protein antibody; apical protein of Xenopus-like antibody; Apical protein Xenopus laevis like antibody; apical protein, Xenopus laevis-like antibody; apical protein-like antibody; apical protein-like (Xenopus laevis) antibody; Apical-like protein antibody; APX homolog of Xenopus antibody; C630003H05Rik antibody; DKFZp781J074 antibody; FLJ39277 antibody; HSAPXL antibody; Liver regeneration-related protein LRRG167 antibody; OTTHUMP00000022887 antibody; Protein Apxl antibody; Protein Shroom2 antibody; Shrm2 antibody; SHRM2_HUMAN antibody; SHROOM 2 antibody; Shroom family member 2 antibody; shroom2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein Shroom2 protein (213-405AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution.

Gene References into Functions

We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 x 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 x 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 x 10(-10)). PMID: 22634755
Data suggest that Shroom2 facilitates the formation of a contractile network within endothelial cells, the loss of which leads to an increase in endothelial sprouting, migration, and angiogenesis. PMID: 21248203

Subcellular Location

Apical cell membrane. Cell junction, tight junction. Cytoplasm, cytoskeleton.

Protein Families

Shroom family

Tissue Specificity

Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.

Database Links

HGNC: 630

OMIM: 300103

KEGG: hsa:357

STRING: 9606.ENSP00000370299

UniGene: Hs.567236

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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