SHROOM2 Antibody, HRP conjugated

Code CSB-PA622684LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SHROOM2 Polyclonal antibody
Uniprot No.
Target Names
SHROOM2
Alternative Names
4832440C16 antibody; Ab2-404 antibody; Apical like protein antibody; Apical like protein APXL protein antibody; apical protein of Xenopus-like antibody; Apical protein Xenopus laevis like antibody; apical protein, Xenopus laevis-like antibody; apical protein-like antibody; apical protein-like (Xenopus laevis) antibody; Apical-like protein antibody; APX homolog of Xenopus antibody; C630003H05Rik antibody; DKFZp781J074 antibody; FLJ39277 antibody; HSAPXL antibody; Liver regeneration-related protein LRRG167 antibody; OTTHUMP00000022887 antibody; Protein Apxl antibody; Protein Shroom2 antibody; Shrm2 antibody; SHRM2_HUMAN antibody; SHROOM 2 antibody; Shroom family member 2 antibody; shroom2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein Shroom2 protein (213-405AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution.
Gene References into Functions
  1. We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 x 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 x 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 x 10(-10)). PMID: 22634755
  2. Data suggest that Shroom2 facilitates the formation of a contractile network within endothelial cells, the loss of which leads to an increase in endothelial sprouting, migration, and angiogenesis. PMID: 21248203
Subcellular Location
Apical cell membrane. Cell junction, tight junction. Cytoplasm, cytoskeleton.
Protein Families
Shroom family
Tissue Specificity
Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.
Database Links

HGNC: 630

OMIM: 300103

KEGG: hsa:357

STRING: 9606.ENSP00000370299

UniGene: Hs.567236

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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