SKOR1 Antibody

Code CSB-PA308064HA01HU
Size US$166
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Image
  • IHC image of CSB-PA308064HA01HU diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SKOR1 Polyclonal antibody
Uniprot No.
Target Names
SKOR1
Alternative Names
SKOR1 antibody; CORL1 antibody; FUSSEL15 antibody; LBXCOR1 antibody; SKI family transcriptional corepressor 1 antibody; Functional Smad-suppressing element on chromosome 15 antibody; Fussel-15 antibody; LBX1 corepressor 1 antibody; Ladybird homeobox corepressor 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human SKI family transcriptional corepressor 1 protein (744-965AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SKOR1 Antibody (Product code: CSB-PA308064HA01HU) is Non-conjugated. For SKOR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA308064HB01HU SKOR1 Antibody, HRP conjugated ELISA
FITC CSB-PA308064HC01HU SKOR1 Antibody, FITC conjugated
Biotin CSB-PA308064HD01HU SKOR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a transcriptional corepressor of LBX1. Inhibits BMP signaling.
Gene References into Functions
  1. Permanent expression of Fussel-15 in keloid and skin sclerosis fibroblasts could be involved in the pathogenesis of these conditions. PMID: 21641385
  2. a novel gene, fussel-15 (functional smad suppressing element on chromosome 15) with high homology to the recently discovered Fussel-18 protein. PMID: 17292623
  3. MEIS1 and LBXCOR1 are developmental factors and raise new pathophysiologic questions for RLS. PMID: 18541116
  4. Observational study of gene-disease association. (HuGE Navigator) PMID: 19822783
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19279021
  6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 17637780

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Subcellular Location
Nucleus.
Protein Families
SKI family
Tissue Specificity
Present specifically in cerebellar Purkinje cells (at protein level).
Database Links

HGNC: 21326

OMIM: 611273

KEGG: hsa:390598

STRING: 9606.ENSP00000369374

UniGene: Hs.451224

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