SLC13A4 Antibody

Code CSB-PA021394GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SLC13A4
Alternative Names
Na(+)/sulfate cotransporter SUT-1 antibody; NaS2 antibody; S13A4_HUMAN antibody; SLC13A4 antibody; Solute carrier family 13 member 4 antibody; SUT1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SLC13A4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV).
Gene References into Functions
  1. Study found that despite differential expression of the two SLC13A4 transcripts, no detectable functional difference in the cellular sorting or sulfate transporting was found. However, some variants can influence both mechanism in specific cell membranes. This is like to have clinical implications based on the consequences of impaired sulfate transport during pregnancy in rodent models. PMID: 28385533
  2. SLC13A4 and SLC26A2 were the most abundant sulfate transporter mRNAs, which localized to syncytiotrophoblast and cytotrophoblast cells, respectively. PMID: 23453247
  3. To investigate the regulation of SLC13A4 gene expression, we analysed the transcriptional activity of the SLC13A4 5'-flanking region in the JEG-3 placental cell line using luciferase reporter assays. PMID: 23485456
  4. Here, we characterized the functional properties of the human Na(+)-sulfate cotransporter (hNaS2), determined its tissue distribution, and identified its gene (SLC13A4) structure. PMID: 15607730
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
SLC13A/DASS transporter (TC 2.A.47) family, NADC subfamily
Tissue Specificity
Highly expressed in placenta and testis with intermediate levels in brain and lower levels in heart, thymus and liver.
Database Links

HGNC: 15827

OMIM: 604309

KEGG: hsa:26266

STRING: 9606.ENSP00000297282

UniGene: Hs.490241

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