SLC31A2 Antibody

Datasheet

Code	CSB-PA021577LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA021577LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA021577LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA021577LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC31A2 Polyclonal antibody

Uniprot No.

O15432

Target Names

SLC31A2

Alternative Names

SLC31A2; COPT2; CTR2; Probable low affinity copper uptake protein 2; Copper transporter 2; hCTR2; Solute carrier family 31 member 2

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable low affinity copper uptake protein 2 protein (44-93AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SLC31A2 Antibody (Product code: CSB-PA021577LA01HU) is Non-conjugated. For SLC31A2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA021577LB01HU	SLC31A2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA021577LC01HU	SLC31A2 Antibody, FITC conjugated
Biotin	CSB-PA021577LD01HU	SLC31A2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in low-affinity copper uptake.

Gene References into Functions

11 single-nucleotide polymorphisms (SNPs) in CTR1, CTR2, ATP7A, and ATP7B were genotyped in these patients. PMID: 28737129
Decreased expression of CTR2 is associated with clear cell renal cell carcinoma. PMID: 26411550
Over-expression of CTR2 increased exchangeable Cu(+) by 150% and rendered the human epithelial 2008 cancer cell model 2.5-fold resistant to cisplatin. PMID: 24522273
Increased CTR2 expression is associated with platinum resistance in epithelial ovarian cancer. PMID: 23564780
hCTR2 is as an oligomeric membrane protein localized in lysosomes, which stimulates copper delivery to the cytosol of human cells at relatively high copper concentrations. PMID: 17617060
Ctr2 promotes copper uptake at the plasma membrane and plays a role in regulating copper levels in COS-7 cells PMID: 17944601
CTR2 functions by limiting drug accumulation, and its expression correlates with the sensitivity of human ovarian carcinoma cell lines to cisplatin. PMID: 19509135

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Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

Copper transporter (Ctr) (TC 1.A.56) family, SLC31A subfamily

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 11017

OMIM: 603088

KEGG: hsa:1318

STRING: 9606.ENSP00000259392

UniGene: Hs.24030

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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