SLC35B4 Antibody

Code CSB-PA853373LA01HU
Size US$166
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  • Immunofluorescent analysis of A2780 cells using CSB-PA853373LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC35B4 Polyclonal antibody
Uniprot No.
Target Names
SLC35B4
Alternative Names
SLC35B4 antibody; YEA4 antibody; PSEC0055 antibody; UDP-xylose and UDP-N-acetylglucosamine transporter antibody; Solute carrier family 35 member B4 antibody; YEA4 homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human UDP-xylose and UDP-N-acetylglucosamine transporter protein (174-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SLC35B4 Antibody (Product code: CSB-PA853373LA01HU) is Non-conjugated. For SLC35B4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA853373LB01HU SLC35B4 Antibody, HRP conjugated ELISA
FITC CSB-PA853373LC01HU SLC35B4 Antibody, FITC conjugated
Biotin CSB-PA853373LD01HU SLC35B4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
Gene References into Functions
  1. Glucose levels activate SLC35B4 expression. This triggers a downstream effect via Hsp60 and other proteins. We hypothesize that the downstream effect on the proteins is mediated via altering the glycosylation pattern inside liver cells PMID: 29867058
  2. subcellular localization of SLC35B4 PMID: 21918738
  3. Decreased SLC35B4 expression led to increased gluconeogenesis in HepG2 cells. PMID: 21507882
  4. Transport capabilities for UDP-Glc and UDP-Xyl were determined with Golgi vesicles isolated from transformed cells PMID: 15911612
Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Protein Families
Nucleotide-sugar transporter family, SLC35B subfamily
Database Links

HGNC: 20584

OMIM: 610923

KEGG: hsa:84912

STRING: 9606.ENSP00000367770

UniGene: Hs.490181

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