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SLC35B4 Antibody, HRP conjugated

Datasheet
Code CSB-PA853373LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC35B4 Polyclonal antibody
Uniprot No.
Q969S0
Target Names
SLC35B4
Alternative Names
SLC35B4 antibody; YEA4 antibody; PSEC0055 antibody; UDP-xylose and UDP-N-acetylglucosamine transporter antibody; Solute carrier family 35 member B4 antibody; YEA4 homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human UDP-xylose and UDP-N-acetylglucosamine transporter protein (174-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
Gene References into Functions
  1. Glucose levels activate SLC35B4 expression. This triggers a downstream effect via Hsp60 and other proteins. We hypothesize that the downstream effect on the proteins is mediated via altering the glycosylation pattern inside liver cells PMID: 29867058
  2. subcellular localization of SLC35B4 PMID: 21918738
  3. Decreased SLC35B4 expression led to increased gluconeogenesis in HepG2 cells. PMID: 21507882
  4. Transport capabilities for UDP-Glc and UDP-Xyl were determined with Golgi vesicles isolated from transformed cells PMID: 15911612
Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Protein Families
Nucleotide-sugar transporter family, SLC35B subfamily
Database Links

HGNC: 20584

OMIM: 610923

KEGG: hsa:84912

STRING: 9606.ENSP00000367770

UniGene: Hs.490181

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