SLC5A11 Antibody

Code CSB-PA021677GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SLC5A11
Alternative Names
homolog of rabbit KST1 antibody; KST1 antibody; Na(+)/myo-inositol cotransporter 2 antibody; na+/myo-inositol cotransporter 2 antibody; putative sodium-coupled cotransporter RKST1 antibody; RKST1 antibody; SC5AB_HUMAN antibody; SGLT6 antibody; SLC5A11 antibody; SMIT2 antibody; Sodium-dependent glucose cotransporter antibody; Sodium/glucose cotransporter KST1 antibody; Sodium/myo-inositol cotransporter 2 antibody; Sodium/myo-inositol transporter 2 antibody; solute carrier family 5 (sodium/glucose cotransporter); member 11 antibody; Solute carrier family 5 member 11 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SLC5A11
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
Gene References into Functions
  1. SLC5A11 is involved with some immune effects and interacts with immune-related gene(s); it is consistent with its function as an autoimmune modifier gene. PMID: 18069935
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Sodium:solute symporter (SSF) (TC 2.A.21) family
Tissue Specificity
Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes.
Database Links

HGNC: 23091

OMIM: 610238

KEGG: hsa:115584

STRING: 9606.ENSP00000289932

UniGene: Hs.164118

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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