SLC6A17 Antibody

Code CSB-PA004745
Size US$100
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  • Western Blot analysis of rat stomach cells using NTT4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
SLC6A17
Alternative Names
SLC6A17 antibody; NTT4 antibody; Sodium-dependent neutral amino acid transporter SLC6A17 antibody; Sodium-dependent neurotransmitter transporter NTT4 antibody; Solute carrier family 6 member 17 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human NTT4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent.
Gene References into Functions
  1. Our genetic findings implicate homozygous SLC6A17 mutations in autosomal-recessive intellectual disability. PMID: 25704603
  2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  3. The substrate profile of the NTT4/XT1-dependent activity is similar to that of the closely related B(0)AT2/SBAT1 (SLC6A15), including a submillimolar apparent affinity for proline and leucine and a low millimolar apparent affinity for glutamine. PMID: 19147495
Involvement in disease
Mental retardation, autosomal recessive 48 (MRT48)
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, postsynapse. Cell junction, synapse, presynapse.
Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A17 subfamily
Database Links

HGNC: 31399

OMIM: 610299

KEGG: hsa:388662

STRING: 9606.ENSP00000330199

UniGene: Hs.128382

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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