SLC6A6 Antibody

1. TauT gene expression is significantly upregulated in mononuclear leukocytes of type 1 diabetes patients and is related to HbA1c levels and inversely to plasma homocysteine. PMID: 26955642
2. CNDP1 and CARNS are expressed in glomeruli and tubular cells; TauT is expressed in renal epithelial cells; CDNP1 may have a role in diabetic neuropathy PMID: 26206726
3. This is the first study to present information on the transcriptional regulation of taurine transporter gene and the localization of the taurine transporter protein in chondrocytic cells. PMID: 25501278
4. Neurotransmitter transporters including SLC6A6 and SLC6A13 mediate the uptake of 5-aminolevulinic acid (ALA) and can play roles in the enhancement of ALA-induced accumulation of protoporphyrin in cancerous cells. PMID: 24842606
5. Immunocytochemistry and flow cytometry analyses revealed that these mAbs recognized the native form of the extracellular domain of SLC6A6 on the cell surface. PMID: 24866236
6. Taurine transporter is a novel pathological marker for stressed motor neurons in amyotrophic lateral sclerosis. PMID: 23180277
7. Taurine transporter deficiency results in aberrant trophoblast turnover and fetal growth restriction. PMID: 23519128
8. Syncytiotrophoblast TauT activity is reduced in maternal obesity and pre-eclampsia compared to normal pregnancy. PMID: 23392873
9. Knockdown of TauT impairs kidney development, possibly through regulation of cell cycle-related genes. PMID: 23392892
10. TauT gene is overexpressed in peripheral blood mononuclear cells of type 2 diabetic patients. PMID: 21739148
11. TNF-alpha-treated cells showed a higher mRNA level of the TAUT (taurine transporter) than did the control cells. PMID: 12062416
12. TauT is involved with p53 in renal development and apoptosis. PMID: 12163498
13. regulation by WT1 PMID: 12681485
14. nitric oxide plays an important role in downregulating microvillous plasma membrane taurine transporter activity in intrauterine growth restriction PMID: 15166008
15. The increased expression level of TAUT mRNA by hypertonicity was repressed by the specific Ca(2+)/CaM kinase II inhibitor. PMID: 15225620
16. TAUT activity in TNF-alpha-treated Caco-2 cells suggests that up-regulation was associated with an increase in the amount of TAUT. PMID: 15630186
17. reporter assay revealed that TNF-alpha-induced TAUT transcriptional activity through the NF-kappaB consensus-like sequence in the human TAUT promoter region PMID: 15907840
18. taurine cotransporter is regulated by oxidative stress and overexpression of aldose reductase and high glucose impair this response PMID: 16356117
19. Greater system beta activity in fetal platelets compared with T lymphocytes is the result of relatively greater TAUT mRNA and protein expression. PMID: 16956961
20. Report taurine transporter activity in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment. PMID: 18703994
21. This study demonstrates the functional coexpression of TauT along with the PAT1 transporter (SLC36A1) at the apical membrane of the intestinal epithelium. PMID: 19074966
22. critical role in protecting against cisplatin-induced nephrotoxicity, possibly by attenuating a p53-dependent pathway PMID: 19423693
23. Glucose reduced taurine transporter (TauT) mRNA and protein in a dose-dependent manner. PMID: 19602579

Show More

Hide All

HGNC: 11052

OMIM: 186854

KEGG: hsa:6533

STRING: 9606.ENSP00000354107

UniGene: Hs.529488