SMARCC2 Antibody

Code CSB-PA851527ESR2HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA851527ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human epityphlon tissue using CSB-PA851527ESR2HU at dilution of 1:100

  • Chromatin Immunoprecipitation Hela (1.1*106) were cross-linked with formaldehyde, sonicated, and immunoprecipitated with 4μg anti-SMARCC2 or a control normal rabbit IgG. The resulting ChIP DNA was quantified using real-time PCR with primers (CSB-PP851527HU) against the ESR1 pS2 promoter.

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) SMARCC2 Polyclonal antibody
Uniprot No. Q8TAQ2
Target Names SMARCC2
Alternative Names BAF 170 antibody; BAF170 antibody; BRG1 associated factor 170 antibody; BRG1-associated factor 170 antibody; Chromatin remodeling complex BAF170 subunit antibody; CRACC 2 antibody; CRACC2 antibody; Mammalian chromatin remodeling complex BRG1 associated factor 170 antibody; Rsc 8 antibody; Rsc8 antibody; SMARCC 2 antibody; Smarcc2 antibody; SMRC2_HUMAN antibody; SWI/SNF complex 170 kDa subunit antibody; SWI/SNF complex subunit SMARCC2 antibody; SWI/SNF related matrix associated actin dependent regulator of chromatin c2 antibody; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily c member 2 antibody; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 antibody; SWI3 like protein antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human SWI/SNF complex subunit SMARCC2 protein (300-650AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, IHC, ChIP
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Native Chromatin Immunoprecipitation(ChIP) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner
Gene References into Functions
  1. BAF170 is important for neurogenesis in embryonic olfactory epithelium. PMID: 27611684
  2. Identification of frameshift mutations in the SMARCC2 gene in gastric and colorectal cancers with microsatellite instability. PMID: 23030715
  3. study finds Baf53 and Baf170 are highly regulated in HIV-1-infected cells PMID: 21699904
Subcellular Location Nucleus
Protein Families SMARCC family
Tissue Specificity Ubiquitously expressed.
Database Links

HGNC: 11105

OMIM: 601734

KEGG: hsa:6601

STRING: 9606.ENSP00000267064

UniGene: Hs.236030

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