SNRPD3 Antibody

Code CSB-PA022335GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SNRPD3
Alternative Names
Sm D3 antibody; Sm-D3 antibody; small nuclear ribonucleoprotein D3 polypeptide 18kDa antibody; Small nuclear ribonucleoprotein Sm D3 antibody; SmD3 antibody; SMD3_HUMAN antibody; snRNP core protein D3 antibody; SNRPD3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SNRPD3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Gene References into Functions
  1. The dimethylated arginine residues play an essential role in the formation of major SmD3 autoepitopes. 1 particular peptide of SmD3 represents a more sensitive and more reliable substrate for the detection of a subclass of anti-Sm antibodies. PMID: 15642139
Subcellular Location
Cytoplasm, cytosol. Nucleus.
Protein Families
SnRNP core protein family
Database Links

HGNC: 11160

OMIM: 601062

KEGG: hsa:6634

STRING: 9606.ENSP00000215829

UniGene: Hs.356549

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