SNUPN Antibody

Datasheet

Code	CSB-PA022350GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

O95149

Target Names

SNUPN

Alternative Names

0610031A09Rik antibody; KPNBL antibody; MGC134006 antibody; MGC95000 antibody; RNA U transporter 1 antibody; RNA, U transporter 1 antibody; RNUT 1 antibody; RNUT1 antibody; SNUPN antibody; Snupn1 antibody; Snurportin 1 antibody; Snurportin-1 antibody; Snurportin1 antibody; SPN1 antibody; SPN1_HUMAN antibody; wu:fc41a03 antibody; zgc:77819 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human SNUPN

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.

Gene References into Functions

Results show that marker rs218966 in gene PHF14 and rs9836027 in MAP4 significantly associated with hypertension; additionally, rare variants in SNUPN significantly associated with systolic blood pressure. PMID: 26866982
analysis of interactions between CRM1 and the nuclear pore protein Tpr and snurportin PMID: 24722547
SPN construct lacking the importin beta binding domain (IBB) localizes primarily to the nucleus rather than to the cytoplasm. PMID: 12095920
There is an interaction between the N- and C-terminal domains of SPN, suggesting an autoregulatory function similar to that of importin-alpha. PMID: 16030253
study presents the crystal structure of the SPN1.CRM1.RanGTP export complex at 2.5 angstrom resolution (where SPN1 is snurportin1 and RanGTP is guanosine 5' triphosphate-bound Ran PMID: 19389996
the binding of dimethylated RNA-caps to snurportin 1 PMID: 19619473

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Subcellular Location

Nucleus. Cytoplasm.

Protein Families

Snurportin family

Database Links

HGNC: 14245

OMIM: 607902

KEGG: hsa:10073

STRING: 9606.ENSP00000309831

UniGene: Hs.21577

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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