SNX12 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA891787LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SNX12 Polyclonal antibody

Uniprot No.

Q9UMY4

Target Names

SNX12

Alternative Names

2610001F05Rik antibody; AW045757 antibody; MGC118982 antibody; MGC118983 antibody; RGD1565585 antibody; RP23-356J7.1 antibody; SDP8 antibody; SNX 12 antibody; SNX12 antibody; SNX12_HUMAN antibody; Sorting nexin 12 antibody; Sorting nexin-12 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Sorting nexin-12 protein (2-172AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

May be involved in several stages of intracellular trafficking.

Gene References into Functions

SNX12 plays a key role in intraluminal vesicle formation and in the maturation of a subpopulation of early endosomes into late endosomes, thereby regulating selective endocytic transport of cargo for degradation. PMID: 28705836
SNX12 protein level is dramatically decreased in the brain of Alzheimer's disease patients as compared to that of controls. PMID: 22709416
find that overexpression of SNX12 restores the sorting process in an Hrs knockdown background. Altogether, our data show that despite lower expression level, SNX12 shares redundant functions with SNX3 in the biogenesis of multivesicular endosomes PMID: 22719997
Metallothionein deficient mice have a marked decrease in Snx12 during acute lung injury PMID: 16166738

Subcellular Location

Membrane; Peripheral membrane protein; Cytoplasmic side.

Protein Families

Sorting nexin family

Database Links

HGNC: 14976

OMIM: 300883

KEGG: hsa:29934

STRING: 9606.ENSP00000363392

UniGene: Hs.260750

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Endocytosis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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