SPINK9 Antibody

Datasheet
Code CSB-PA707717LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q5DT21
Image
  • IHC image of CSB-PA707717LA01HU diluted at 1:400 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Serine protease inhibitor Kazal-type 9 protein (20-86AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:200-1:500
Relevance Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Serine protease inhibitor Kazal-type 9 (Lymphoepithelial Kazal-type-related inhibitor 2), SPINK9, LEKTI2
Immunogen Species Human
Research Area Signal Transduction
Target Names SPINK9
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5.
Subcellular Location Secreted
Tissue Specificity Skin. Highly expressed at sites of hyperkeratosis. Also detected in thymus, tonsils, testis, pancreas, liver, placenta and brain. Expressed at stratum granulosum and stratum corneum at palmar and plantar sites (at protein level).
Database Links

HGNC: 32951

OMIM: 613511

KEGG: hsa:643394

STRING: 9606.ENSP00000367139

UniGene: Hs.631798

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