SRP72 Antibody, HRP conjugated

Code CSB-PA334457HB01SVG
Size US$166
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SRP72 Polyclonal antibody
Uniprot No.
Target Names
SRP72
Alternative Names
SRP72 antibody; YPL210CSignal recognition particle subunit SRP72 antibody; Signal recognition particle 72 kDa protein homolog antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae
Immunogen
Recombinant Saccharomyces cerevisiae Signal recognition particle subunit SRP72 protein (1-180AA)
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP72 binds the 7S RNA only in presence of SRP68.
Gene References into Functions
  1. Srp72p has at least two functions that are individually redundant and that the conformation of the complex is critical for efficient completion of its biogenesis. PMID: 18418087
Subcellular Location
Cytoplasm. Endoplasmic reticulum membrane. Nucleus. Note=Transiently localizes to the nucleolus during biogenesis of the SRP. The SRP-RNC complex is bound to the endoplasmic reticulum membrane due to the interaction of the SRP with the membrane SRP-receptor (SRP101-SRP102).
Protein Families
SRP72 family
Database Links

KEGG: sce:YPL210C

STRING: 4932.YPL210C

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