SSBP2 Antibody

1. The minor allele of SSBP2 SNP rs17296479 and the increased tumor expression of SSBP2 were statistically significantly associated with poorer overall survival among glioblastoma patients PMID: 22472174
2. results indicate that cigarette smoking is a cause of SSBP2 promoter methylation and that SSBP2 harbors a tumor suppressive role in ESCC through inhibition of the Wnt signaling pathway PMID: 20658532
3. Member of a closely related, evolutionarily conserved, and ubiquitously expressed gene family, potential tumor suppressor PMID: 12079286
4. Our findings are consistent with human SSBP2 being a novel regulator of hematopoietic growth and differentiation, whose loss confers a block in differentiation advantage to myeloid leukemic cells. PMID: 15782145
5. Results suggest that subverting SSBP2 function by oncoprotein E1B55K may contribute to cell transformation by viral oncoproteins. PMID: 17311003
6. SSBP2 inhibits prostate cancer cell proliferation and seems to represent a novel prostate cancer-specific DNA marker, especially in high stages of human prostate cancer. PMID: 18559593
7. SSBP2-JAK2 fusion gene resulting from a t(5;9)(q14.1;p24.1) is associated with pre-B acute lymphocytic leukemia. PMID: 18618714
8. ZNF198-FGFR1 is associated with phosphorylation of several proteins including SSBP2, ABL, FLJ14235, CALM and TRIM4 proteins. PMID: 19658100

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HGNC: 15831

OMIM: 607389

KEGG: hsa:23635

STRING: 9606.ENSP00000322977

UniGene: Hs.102735