SSH1 Antibody, FITC conjugated

Datasheet
Code CSB-PA837881LC01HU
Size US$299
Uniprot No. Q8WYL5
Immunogen Recombinant Human Protein phosphatase Slingshot homolog 1 protein (928-1049AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Protein phosphatase Slingshot homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 1) (SSH-1L) (hSSH-1L), SSH1, KIAA1298 SSH1L
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Signal Transduction
Target Names SSH1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Subcellular Location Cytoplasm, cytoskeleton, Cell projection, lamellipodium, Cleavage furrow, Midbody
Protein Families Protein-tyrosine phosphatase family
Database Links

HGNC: 30579

OMIM: 606778

KEGG: hsa:54434

STRING: 9606.ENSP00000315713

UniGene: Hs.199763

Pathway Regulation of actin cytoskeleton

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