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ST3GAL3 Antibody, FITC conjugated

Datasheet
Code CSB-PA606136LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ST3GAL3 Polyclonal antibody
Uniprot No.
Q11203
Target Names
ST3GAL3
Alternative Names
3 sialyltransferase antibody; 3(4) GlcNAc alpha-2 antibody; 3-sialyltransferase 3 antibody; 3-sialyltransferase antibody; 3-ST 3 antibody; 4-galactoside alpha-2 antibody; 4GlcNAc alpha 2 3 sialyltransferase antibody; Alpha 2 3 sialyltransferase II antibody; Alpha 2 3 sialyltransferase III antibody; Alpha 2 3 ST 3 antibody; Alpha 2 antibody; Beta galactoside alpha 3 sialyltransferase 3 antibody; Beta-galactoside alpha-2 antibody; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase antibody; CMP-N-acetylneuraminate-beta-1 antibody; EC 2.4.99.6 antibody; Gal beta 1 3 antibody; Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta-1 antibody; N acetyllactosaminide alpha 2 3 sialyltransferase antibody; N-acetyllactosaminide alpha-2 antibody; OTTHUMP00000008820 antibody; OTTHUMP00000008821 antibody; OTTHUMP00000008822 antibody; OTTHUMP00000008823 antibody; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase) antibody; Sialyltransferase 6 antibody; SIAT6 antibody; SIAT6_HUMAN antibody; ST3 beta galactoside alpha 2 3 sialyltransferase 3 antibody; ST3 beta galactoside alpha 2,3 sialyltransferase 3 antibody; ST3Gal III antibody; St3gal3 antibody; ST3GALII antibody; ST3GalIII antibody; ST3N antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase protein (29-375AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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ST3GAL3 Antibodies

ST3GAL3 Proteins

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Target Background

Function
Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.
Gene References into Functions
  1. CA19.9 appears as a physiological product whose synthesis strongly depends on the tissue specific and epigenetically-regulated expression of B3GALT5 and ST3GAL3. PMID: 27535614
  2. ST3Gal3 knockdown synergistically enhanced cisplatin-induced apoptosis in ovarian cancer cells PMID: 27871859
  3. ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules. PMID: 27779707
  4. Dysfunctional ST3GAL3 may result in perturbation of the posttranslational sialylation of proteins in these pathways PMID: 23252400
  5. ST3GAL3 mutations impair the development of higher cognitive functions. PMID: 21907012
  6. Characterization of the promoter region of the ST3Gal III gene. PMID: 12697334
  7. 19 different transcripts of ST3GalIII were isolated and cloned; tissue distribution analysis showed complex patterns in neural and muscular tissues PMID: 12815231
  8. High levels of ST3GAL-III in the tumor tissue correlated with secondary local tumor recurrence (p = 0.005; p = 0.012). PMID: 12931020
  9. Identification of a new ST3Gal3 transcript from fetal brain. PMID: 15316282

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Involvement in disease
Mental retardation, autosomal recessive 12 (MRT12); Epileptic encephalopathy, early infantile, 15 (EIEE15)
Subcellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Protein Families
Glycosyltransferase 29 family
Tissue Specificity
Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.
Database Links

HGNC: 10866

OMIM: 606494

KEGG: hsa:6487

UniGene: Hs.597915

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