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ST3GAL6 Antibody

Datasheet
Code CSB-PA022756GA01HU
Size $600
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Product Details

Uniprot No.
Q9Y274
Target Names
ST3GAL6
Alternative Names
ibody; 3-sialyltransferase VI antibody; alpha-2,3-sialyltransferase VI antibody; alpha2,3-sialyltransferase antibody; CMP-NeuAc:beta-galactoside alpha-2 antibody; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI antibody; SIA10_HUMAN antibody; Sialyltransferase 10 antibody; ST3Gal VI antibody; ST3GAL6 antibody; ST3GalVI antibody; Type 2 lactosamine alpha-2,3-sialyltransferase antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ST3GAL6
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
Gene References into Functions
  1. The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma. PMID: 25061176
  2. the occurrence of CD75s- and iso-CD75s-gangliosides in tumor tissues is largely independent of the transcriptional expression of ST6GAL1 and ST3GAL6 PMID: 21147760
  3. Expression of ST3Gal IV in several gastrointestinal cell lines is correlated with the expression of sialyl Lewis x at the cell surface. PMID: 19781661
  4. Epigenetic changes in a group of glycosyltransferases including B4GALNT2 and ST3GAL6 represent a malignant phenotype of gastric cancer caused by silencing of the activity of these enzymes PMID: 18485915
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 29 family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 18080

OMIM: 607156

KEGG: hsa:10402

STRING: 9606.ENSP00000377717

UniGene: Hs.148716

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