ST6GALNAC1 Antibody

Code CSB-PA868312LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western Blot
    Positive WB detected in: HepG2 whole cell lysate
    All lanes: ST6GALNAC1 antibody at 2.7μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 69 kDa
    Observed band size: 69 kDa

  • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA868312LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA868312LA01HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ST6GALNAC1 Polyclonal antibody
Uniprot No. Q9NSC7
Target Names ST6GALNAC1
Alternative Names 6-sialyltransferase 1 antibody; 6-sialyltransferase I antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase antibody; Alpha-N-acetylgalactosaminide alpha-2 antibody; GalNAc alpha 2 6 sialyltransferase I antibody; GalNAc alpha-2 antibody; HSY11339 antibody; SIA7A_HUMAN antibody; Sialyltransferase 7A antibody; SIAT7-A antibody; SIAT7A antibody; ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; ST6GalNAc I antibody; ST6GALNAC1 antibody; ST6GalNAcI antibody; STYI antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 protein (36-249AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Our results indicated that ST6GALNAC1 was downregulated in sporadic esophageal squamous cell carcinoma via hyper-methylation and loss of heterozygosity , and it may be a candidate responsible gene for esophageal squamous cell carcinoma PMID: 28035351
  2. ST6GalNAc I regulates the gene expression of IGF-1 through STAT5b activation and plays role in gastric cancer invasion and metastasis. PMID: 25532910
  3. upregulated Siat7A expression, which was paralleled by the increased Klf4 in the ischemic myocardium, contributed to cardiomyocyte apoptosis following myocardial infarction PMID: 25860962
  4. Using qRT-PCR, sialyl-Tn expression was found to be associated with an increase in alpha2,6-sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in LS174T cells. PMID: 24840470
  5. It was confirmed that MUC1 carries sialyl Tn also in human advanced gastric cancer tissues PMID: 22228572
  6. The stable transfection of MDA-MB-231 with an expression vector encoding ST6GalNAc I induces the expression of STn antigen at the cell surface. PMID: 12820722
  7. ST6GalNAc-I sialyltransferase localizes throughout the Golgi and has a role in synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer PMID: 16319059
  8. Expression of ppGalNAc-T6 is significantly higher in breast cancer compared to 'normal'/benign breast tissue samples. ST6GalNAc-I expression in breast cancer is associated with better prognosis. PMID: 19287074

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Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 29 family
Database Links

HGNC: 23614

OMIM: 610138

KEGG: hsa:55808

STRING: 9606.ENSP00000156626

UniGene: Hs.105352

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