ST8SIA2 Antibody

1. The ST8SIA2 risk haplotype copy number did not show any differential effects on white matter in schizophrenia. PMID: 29353880
2. impairment of the regulated expression of ST8SIA2 and the resulting downstream effects on gene products by these two intronic single nucleotide polymorphism contribute to the development of these psychiatric disorders. PMID: 27565727
3. ST8SiaII role in the invasiveness and metastasis of small cell lung cancer cells PMID: 28004110
4. the relationships between psychiatric disorders and polySia and/or ST8SIA2 PMID: 27105834
5. Data indicate a possible role of STX polysialyltransferase (ST8SIA2) in the common susceptibility of schizophrenia and bipolar I disorder (BD-I). PMID: 26418860
6. Our study showed interesting sex-specific associations between ST8SIAII and schizophrenia. PMID: 24070986
7. the role of ST8SIA2 sequence variation affecting polysialic acid-NCAM formation in 48 Caucasian cases with bipolar disorder PMID: 24651862
8. translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII in mammalian semen involves polysialic acid PMID: 23671285
9. Expression of ST8SIA2 in omental fat at baseline was significantly associated with weight loss after Roux-en-Y gastric bypass. PMID: 23643386
10. that variation the ST8SIA2 gene is associated with increased risk to mental illness PMID: 22693595
11. NCAM and polySia are expressed and developmentally regulated in chick corneas. Both membrane-associated and soluble NCAM isoforms are expressed in chick corneas. PMID: 22281821
12. ST8SIA2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
13. STX(G421A) shows a dramatic decrease in polySia synthetic activity on NCAM, whereas STX(C621G) does not; polySia shows a dopamine (DA) binding activity PMID: 21464126
14. This study provided that ST8SIA2 are associated with Bipolar I in the Han Chinese population. PMID: 20386566
15. SIAT8B has a role in neural development and sialic acid synthesis on NCAM PMID: 12138100
16. SIAT8B gene is involved in schizophrenia in the Japanese. PMID: 16229822

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HGNC: 10870

OMIM: 602546

KEGG: hsa:8128

STRING: 9606.ENSP00000268164

UniGene: Hs.302341