STH Antibody, Biotin conjugated

1. Saitohin Q7R polymorphism is associated with late-onset Alzheimer's disease susceptibility among caucasian populations. (Meta-analysis) PMID: 28211174
2. Results showed a significant interaction effect of COMT and STH polymorphisms on cognitive performances, strengthening the involvement of STH in cognitive impairments, especially in the domains commonly impaired in schizophrenia PMID: 25283873
3. The rs6203857 polymorphism of the saitohin gene is a genetic risk factor for Parkinson's disease. PMID: 25168738
4. results of this meta-analysis suggested that MAPT_238bp/STH Q7R polymorphisms might modulate the risk of Parkinson's disease susceptibility PMID: 25305495
5. These results suggest a possible contribution of STH gene products on the heterogeneity of core frontal executive functions deterioration in schizophrenia PMID: 22187337
6. Single polymorphisms within the saitohin gene were associated with increased cognitive impairment and functional dependence persons with moderate-to-advanced Alzheimer disease. PMID: 21934306
7. effect of Saitohin on Abl-mediated phosphorylation appears to be allele-specific, providing evidence for a new cellular function for STH PMID: 21769920
8. STH polymorphisms play a possibly shared role with those of serotinin transporter 5-HTTLPR gene as a susceptibility factor for Alzheimer's disease and frontotemperal lobar dementia. PMID: 20852909
9. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20852909
10. a gene within an intron of the tau gene; Q7R polymorphism appears to be over-represented in the homozygous state in late onset Alzheimer's disease subjects PMID: 12032355
11. The saitohin Q allele, a novel determinant of tau H1 haplotypes, may represent a causative factor involved in the determinism of several tauopathies, e.g., frontotemporal dementia. PMID: 12447938
12. At the STH gene only a common polymorphic change was found. PMID: 12826737
13. Increased risk of Alzheimer's disease associated with the STH RR genotype is limited to late-onset Alzheimer's disease. PMID: 12826738
14. The R allele of STH is associated with the H2 haplotype of tau; no correlation is found between R allele frequency and Alzheimer's or Parkinson's disease. PMID: 12932819
15. Saitohin interacts with peroxiredoxin 6, a unique member of that family that is bifunctional and the levels of which increase in Pick disease. PMID: 16186110
16. We found no evidence that could support a major pathogenic role of STH and TAU haplotype in AD, FTD or PD. PMID: 16909000
17. Q allele of STH gene is over-represented in a tested group of patients with Huntington disease and might be considered a risk factor for HD like diseases. PMID: 18300012
18. Homozygous Q/Q of STH Q7R polymorphism was the only one genotype found in either LOAD group or controls. No R allele was detected in LOAD and control groups. PMID: 18396294
19. The Saitohin Q7R polymorphism is unlikely to contribute significantly to Alzheimer's disease susceptibility of the Han population in south China. PMID: 18850062
20. Observational study of gene-disease association. (HuGE Navigator) PMID: 18850062
21. Observational study of gene-disease association. (HuGE Navigator) PMID: 18509094
22. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 18396294
23. Observational study of genotype prevalence. (HuGE Navigator) PMID: 18300012
24. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 18307033
25. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 15136700
26. Observational study of gene-disease association. (HuGE Navigator) PMID: 16603077
27. Observational study of gene-disease association. (HuGE Navigator) PMID: 16909000

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HGNC: 18839

OMIM: 607067

KEGG: hsa:246744

STRING: 9606.ENSP00000443168

UniGene: Hs.661831