STK17A Antibody

Datasheet

Code	CSB-PA022837GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q9UEE5

Target Names

STK17A

Alternative Names

DAP kinase-related apoptosis-inducing protein kinase 1 antibody; death-associated protein kinase-related 1 antibody; DRAK1 antibody; EC 2.7.11.1 antibody; Serine / threonine kinase 17a death associated protein kinase related 1 antibody; Serine/threonine kinase 17a antibody; Serine/threonine protein kinase 17a antibody; Serine/threonine-protein kinase 17A antibody; ST17A_HUMAN antibody; STK17 A antibody; STK17A antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Human STK17A

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.

Gene References into Functions

These findings suggest that DRAK1 translocates in response to stimuli and induces apoptosis through its interaction with specific binding partners, p53 and/or ANT2. PMID: 29397938
the present study was the first to find localization of STK17A in normal bile canaliculi. PMID: 26305096
DRAK1 was predominantly localized in the cytoplasm and bound to Smad3, thereby interrupting Smad3/Smad4 complex formation, which is the core process for the induction of tumor suppressor genes by TGF-beta1 PMID: 25531329
STK17A provides a proliferative and survival advantage to GBM cells PMID: 24312360
When analyzing STK17A haplotypes distribution, we found association between TGGTC, TAGTC and AAGAT haplotypes and risk to develop SLE PMID: 23860322
identified STK17A as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. PMID: 21489989

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Subcellular Location

Nucleus.

Protein Families

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily

Tissue Specificity

Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.

Database Links

HGNC: 11395

OMIM: 604726

KEGG: hsa:9263

STRING: 9606.ENSP00000319192

UniGene: Hs.709489

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Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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