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SULT1C2 Antibody

Datasheet
Code CSB-PA022938GA01HU
Size $600
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Product Details

Uniprot No.
O00338
Target Names
SULT1C2
Alternative Names
humSULTC2 antibody; ST1C1 antibody; ST1C2 antibody; ST1C2_HUMAN antibody; Sulfotransferase 1C1 antibody; Sulfotransferase 1C2 antibody; Sulfotransferase family cytosolic 1C member 1 antibody; Sulfotransferase family cytosolic 1C member 2 antibody; SULT1C#1 antibody; SULT1C1 antibody; SULT1C2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human SULT1C2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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SULT1C2 Proteins

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Target Background

Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Sulfonates p-nitrophenol, a small phenolic compond. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol. Catalyzes the sulfonation of the carcinogenic N-Hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis.
Gene References into Functions
  1. Vitamin D receptor can interact directly with the SULT1C2 VDRE sequence to transcriptionally regulation SULT1C2 expression in colorectal tumor cells. PMID: 27130351
  2. Our findings are the first to characterize the regulation of human SULT1C2 and SULT1C3 expression by several transcription factor activators. PMID: 24335393
  3. gene resequencing and functional genomic studies PMID: 11740338
  4. crystal structures of two members of SULT1 family, SULT1B1 and SULT1C1, both in complex with the product of the PAPS cofactor, adenosine-3-5-diphosphate (PAP). PMID: 16804942
Subcellular Location
Cytoplasm. Lysosome.
Protein Families
Sulfotransferase 1 family
Tissue Specificity
Found in adult stomach, kidney and thyroid gland, and in fetal kidney and liver.
Database Links

HGNC: 11456

OMIM: 602385

KEGG: hsa:6819

UniGene: Hs.436123

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