SYCE1 Antibody

Code CSB-PA022987ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: SYCE1 antibody at 1.14μg/ml + Mouse liver tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 40, 33, 22 kDa
    Observed band size: 40, 58 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA022987ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SYCE1 Polyclonal antibody
Uniprot No.
Target Names
SYCE1
Alternative Names
SYCE1 antibody; C10orf94 antibody; Synaptonemal complex central element protein 1 antibody; Cancer/testis antigen 76 antibody; CT76 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Synaptonemal complex central element protein 1 protein (132-351AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination.
Gene References into Functions
  1. A mutation in SYCE1 is associated with non-obstructive azoospermia. PMID: 25899990
  2. Given the known function of the SYCE1 gene, we suggest that the nonsense mutation identified accounts for the primary ovarian insufficiency phenotype. PMID: 25062452
Involvement in disease
Premature ovarian failure 12 (POF12); Spermatogenic failure, 15 (SPGF15)
Subcellular Location
Nucleus. Chromosome.
Protein Families
SYCE family
Database Links

HGNC: 28852

OMIM: 611486

KEGG: hsa:93426

STRING: 9606.ENSP00000341282

UniGene: Hs.553795

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