SYNJ2 Antibody

1. Results, combined with previous studies, suggest that rs9365723, located on SYNJ2, is associated with the risk of CRC in a Chinese population. PMID: 26616230
2. Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer. PMID: 25605973
3. The genetic interactions associated with ILVatrophy rate in this study may be mapping variants inSYNJ2andPI4KAthat interact to decrease synthesisof PIP. PMID: 24077433
4. Src-mediated phosphorylation of SYNJ2 contributes to invadopodia formation. PMID: 23076136
5. SYNJ2 is a novel gene in which variation is potentially associated with cognitive abilities. PMID: 22045296
6. Single nucleotide polymorphisms in SYNJ2 are associated with personality disorders. PMID: 22213687
7. SYNJ2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
8. Since Syn 2 is a phosphatidylinositol 4,5-biphosphatase involved in cell growth and rearrangement of actin filaments, the increased Syn 2 expression may correlate with the hairy cell leukemia etiology or the characteristic morphologic alterations. PMID: 14562116
9. contributes to the role of Rac1 in cell invasion and migration by regulating the formation of invadopodia and lamellipodia PMID: 15548694
10. Identification of inactivating mutations in the JAK1, SYNJ2, and CLPTM1 genes in prostate cancer cells PMID: 16102578

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HGNC: 11504

OMIM: 609410

KEGG: hsa:8871

STRING: 9606.ENSP00000347792

UniGene: Hs.434494