TAF1C Antibody

Code CSB-PA620884ESR1HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: TAF1C antibody at 2μg/ml + 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 96, 85, 59, 50, 93 kDa
    Observed band size: 96 kDa

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA620884ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA620884ESR1HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TAF1C Polyclonal antibody
Uniprot No. Q15572
Target Names TAF1C
Alternative Names RNA polymerase I-specific TBP-associated factor 110 kDa antibody; SL1 antibody; Taf1c antibody; TAF1C_HUMAN antibody; TAFI110 antibody; TAFI95 antibody; TATA box binding protein associated factor 1C antibody; TATA box-binding protein-associated factor 1C antibody; TATA box-binding protein-associated factor RNA polymerase I subunit C antibody; TBP associated factor 1C antibody; TBP associated factor RNA polymerase I 95 kDa antibody; TBP associated factor; RNA polymerase I; 110-KD antibody; TBP-associated factor 1C antibody; Transcription initiation factor SL1/TIF-IB subunit C antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human TATA box-binding protein-associated factor RNA polymerase I subunit C protein (70-320AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Gene References into Functions
  1. Our results indicate that TAF1C gene harboured not only somatic frameshift mutations but also the mutational ITH, which together might play a role in tumourigenesis of gastric and colorectal cancer. PMID: 25551296
  2. PTEN represses RNA Pol I transcription through a novel mechanism that involves disruption of the SL1 complex PMID: 16055704
Subcellular Location Nucleus
Database Links

HGNC: 11534

OMIM: 604905

KEGG: hsa:9013

STRING: 9606.ENSP00000367802

UniGene: Hs.153022

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