TAF6L Antibody, FITC conjugated

Datasheet

Code	CSB-PA896758LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TAF6L Polyclonal antibody

Uniprot No.

Q9Y6J9

Target Names

TAF6L

Alternative Names

TAF6L antibody; PAF65A antibody; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L antibody; TAF6L antibody; PCAF-associated factor 65-alpha antibody; PAF65-alpha antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L protein (345-433AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF5L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state. Functions with MYC to activate target gene expression through RNA polymerase II pause release.

Gene References into Functions

immunohistochemical studies suggest that CBP, depending on the balance of nuclear proteins, is a component of AIRE nuclear bodies PMID: 15964547
protein kinase C betaII augments NF-kappaB-mediated TNF-alpha-induced transcription of the target gene CCL11, promoting p65 association with the CCL11 promoter, in human airway smooth muscle cells by phosphorylating p300/CBP-associated factor PMID: 18714023

Subcellular Location

Nucleus.

Protein Families

TAF6 family

Database Links

HGNC: 17305

OMIM: 602946

KEGG: hsa:10629

STRING: 9606.ENSP00000294168

UniGene: Hs.714400

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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