TAF6L Antibody

Code CSB-PA896758LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA896758LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAF6L Polyclonal antibody
Uniprot No.
Target Names
TAF6L
Alternative Names
TAF6L antibody; PAF65A antibody; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L antibody; TAF6L antibody; PCAF-associated factor 65-alpha antibody; PAF65-alpha antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L protein (345-433AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TAF6L Antibody (Product code: CSB-PA896758LA01HU) is Non-conjugated. For TAF6L Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA896758LB01HU TAF6L Antibody, HRP conjugated ELISA
FITC CSB-PA896758LC01HU TAF6L Antibody, FITC conjugated
Biotin CSB-PA896758LD01HU TAF6L Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF5L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state. Functions with MYC to activate target gene expression through RNA polymerase II pause release.
Gene References into Functions
  1. immunohistochemical studies suggest that CBP, depending on the balance of nuclear proteins, is a component of AIRE nuclear bodies PMID: 15964547
  2. protein kinase C betaII augments NF-kappaB-mediated TNF-alpha-induced transcription of the target gene CCL11, promoting p65 association with the CCL11 promoter, in human airway smooth muscle cells by phosphorylating p300/CBP-associated factor PMID: 18714023
Subcellular Location
Nucleus.
Protein Families
TAF6 family
Database Links

HGNC: 17305

OMIM: 602946

KEGG: hsa:10629

STRING: 9606.ENSP00000294168

UniGene: Hs.714400

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