TAS2R39 Antibody

Code CSB-PA004217
Size US$119
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  • Western Blot analysis of HepG2 cells using T2R39 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
Alternative Names
TAS2R39; Taste receptor type 2 member 39; T2R39; Taste receptor type 2 member 57; T2R57
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human T2R39.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Gene References into Functions
  1. hTAS2R39 is the primary receptor for the bitterness of theaflavins PMID: 25273142
  2. TAS2R14 and TAS2R39 were activated by isoflavones and other isoflavonoids. PMID: 21942422
  3. Human bitter taste receptors hTAS2R8 and hTAS2R39 display differential functions to recognize bitter peptides. PMID: 21670512
  4. these results suggest the participation of hTAS2R39 in the detection of catechins in humans. PMID: 21272567
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor T2R family
Tissue Specificity
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Database Links

HGNC: 18886

KEGG: hsa:259285

STRING: 9606.ENSP00000405095

UniGene: Hs.553660

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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