TBX18 Antibody

1. Tbx18-positive cells represent a part of PE cells in the initial phase of differentiation and subsequently include SMCs as well as fibroblasts. These results indicate that Tbx18-positive cells serve as a PE progenitor to supply a variety of cells that contribute to the formation of coronary arteries. PMID: 28794400
2. Gene product expressions of SHH, TBX18 and TSHZ3 are statistically higher in patients with UPJ obstruction, when compared with control group. The explanation may be the reactivation of the processes, which had shown their effects in the embryological period, due to the chronic inflammation and long-term micro-trauma created by the disease PMID: 27381532
3. Data indicate that human T-box 18 (TBX18) gene induces rat adipose-derived stem cells (ADSCs) to differentiate into pacemaker-like cells in the cardiac microenvironment. PMID: 27632938
4. Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development. PMID: 26235987
5. The DNA sequence variants within the TBX18 gene promoter identified in ventricular septal defects (VSD) patients may be involved in the VSD etiology. PMID: 23749171
6. connexin43 transcriptional suppression by TBX18 undermines cardiomyocyte cell-cell electrical coupling PMID: 21205823
7. Tbx18 interacts with Gata4 and Nkx2-5 and competes Tbx5-mediated activation of the cardiac Natriuretic peptide precursor type a-promoter. Tbx18 down-regulates Tbx6-activated Delta-like 1 expression in the somitic mesoderm in vivo PMID: 17584735

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HGNC: 11595

OMIM: 143400

KEGG: hsa:9096

STRING: 9606.ENSP00000358677

UniGene: Hs.251830