ELOA Antibody

Datasheet

Code	CSB-PA619867ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA619867ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA619867ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ELOA Polyclonal antibody

Uniprot No.

Q14241

Target Names

ELOA

Alternative Names

Ela1 antibody; Elo A antibody; EloA antibody; ELOA1_HUMAN antibody; Elongin 110 kDa subunit antibody; Elongin-A antibody; ElonginA antibody; RNA polymerase II transcription factor SIII subunit A1 antibody; SIII antibody; SIII p110 antibody; TCEB 3 antibody; Tceb3 antibody; TCEB3A antibody; Transcription elongation factor B (SIII) polypeptide 3 (110kD) antibody; Transcription elongation factor B (SIII) polypeptide 3 antibody; Transcription elongation factor B alpha subunit antibody; Transcription elongation factor B polypeptide 3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Elongin-A protein (679-798AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).

Gene References into Functions

the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage PMID: 28292928
TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors PMID: 24351681
Elongin A transcription elongation activity, but not its ubiquitination activity, is most important for its function in induction of transcription of ATF3 and p21. PMID: 23828199

Subcellular Location

Nucleus.

Database Links

HGNC: 11620

OMIM: 600786

KEGG: hsa:6924

STRING: 9606.ENSP00000395574

UniGene: Hs.15535

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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