TCEB3 Antibody

Datasheet

Code	CSB-PA023286GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q14241

Target Names

ELOA

Alternative Names

Ela1 antibody; Elo A antibody; EloA antibody; ELOA1_HUMAN antibody; Elongin 110 kDa subunit antibody; Elongin-A antibody; ElonginA antibody; RNA polymerase II transcription factor SIII subunit A1 antibody; SIII antibody; SIII p110 antibody; TCEB 3 antibody; Tceb3 antibody; TCEB3A antibody; Transcription elongation factor B (SIII) polypeptide 3 (110kD) antibody; Transcription elongation factor B (SIII) polypeptide 3 antibody; Transcription elongation factor B alpha subunit antibody; Transcription elongation factor B polypeptide 3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human TCEB3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).

Gene References into Functions

the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage PMID: 28292928
TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors PMID: 24351681
Elongin A transcription elongation activity, but not its ubiquitination activity, is most important for its function in induction of transcription of ATF3 and p21. PMID: 23828199

Subcellular Location

Nucleus.

Database Links

HGNC: 11620

OMIM: 600786

KEGG: hsa:6924

STRING: 9606.ENSP00000395574

UniGene: Hs.15535

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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