TCP10L Antibody

Code CSB-PA023322GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TCP10L
Alternative Names
TCP10L antibody; PRED77 antibody; T-complex protein 10A homolog 1 antibody; T-complex protein 10A-1 antibody; TCP10A-1 antibody; TCP10-like antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human TCP10L
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells.
Gene References into Functions
  1. TCP10L stabilizes MAD1 protein level through direct interaction, and they cooperatively regulate cell cycle progression. PMID: 26698869
  2. Overexpression of TCP10L in hepatocellular carcinoma cells suppressed colony formation, inhibited cell cycle progression through G0/G1 phase, and attenuated cell growth in vivo. PMID: 24565846
  3. The result revealed that TCP10L expressed specifically in the human liver and testis PMID: 14586771
  4. Data suggest that the biological function of the interaction between T-complex protein 10-like and MAD4 may be to maintain the differentiation state in liver cells. PMID: 15469726
  5. The specific expression pattern of TCP10L and interaction with DAPK-3 implies that TCP10L might play crucially important roles in spermatogenesis through its interaction with DAPK-3. PMID: 15910542

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Subcellular Location
Nucleus.
Protein Families
TCP10 family
Tissue Specificity
Expressed in liver and testis. Expressed in the seminiferous tubules (at protein level).
Database Links

HGNC: 11657

OMIM: 608365

KEGG: hsa:140290

STRING: 9606.ENSP00000300258

UniGene: Hs.728804

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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