TCTA Antibody, FITC conjugated

Code CSB-PA023331LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TCTA Polyclonal antibody
Uniprot No.
Target Names
TCTA
Alternative Names
T-cell leukemia translocation altered gene antibody; T-cell leukemia translocation-altered gene protein antibody; T-cell leukemia translocation-associated gene protein antibody; Tcta antibody; TCTA_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human T-cell leukemia translocation-altered gene protein (62-103AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be required for cellular fusion during osteoclastogenesis.
Gene References into Functions
  1. TCTA protein has roles in lung cancer cell lines and human osteoclastogenesis [review] PMID: 22174563
  2. It expressed in synovial tissues from patients with RA and inhibits human osteoclastogenesis. (review) PMID: 20046013
  3. TCTA is a novel protein expressed in synovial tissues of rheumatoid arthritis that regulate human osteoclastogenesis. PMID: 19560569
Involvement in disease
A chromosomal aberration involving TCTA is associated with T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(1;3)(p34;p21).
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
TCTA family
Tissue Specificity
Ubiquitous. Highest level of expression in kidney. Present in monocytes, osteoclasts, macrophages, synoviocytes and synovial lining cells (at protein level).
Database Links

HGNC: 11692

OMIM: 600690

KEGG: hsa:6988

STRING: 9606.ENSP00000273590

UniGene: Hs.517962

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