TCTA Antibody

Datasheet

Code	CSB-PA023331LA01HU
Size	US$166
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Image	Western blot All lanes: TCTA antibody at 1.6µg/ml Lane 1: Mouse liver tissue Lane 2: Mouse gonadal tissue Lane 3: Mouse muscle tissue Lane 4: HL60 whole cell lysate Lane 5: U251 whole cell lysate Lane 6: MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 12 kDa Observed band size: 12 kDa Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA023331LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023331LA01HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TCTA Polyclonal antibody

Uniprot No.

P57738

Target Names

TCTA

Alternative Names

T-cell leukemia translocation altered gene antibody; T-cell leukemia translocation-altered gene protein antibody; T-cell leukemia translocation-associated gene protein antibody; Tcta antibody; TCTA_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human T-cell leukemia translocation-altered gene protein (62-103AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TCTA Antibody (Product code: CSB-PA023331LA01HU) is Non-conjugated. For TCTA Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA023331LB01HU	TCTA Antibody, HRP conjugated	ELISA
FITC	CSB-PA023331LC01HU	TCTA Antibody, FITC conjugated
Biotin	CSB-PA023331LD01HU	TCTA Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

May be required for cellular fusion during osteoclastogenesis.

Gene References into Functions

TCTA protein has roles in lung cancer cell lines and human osteoclastogenesis [review] PMID: 22174563
It expressed in synovial tissues from patients with RA and inhibits human osteoclastogenesis. (review) PMID: 20046013
TCTA is a novel protein expressed in synovial tissues of rheumatoid arthritis that regulate human osteoclastogenesis. PMID: 19560569

Involvement in disease

A chromosomal aberration involving TCTA is associated with T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(1;3)(p34;p21).

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

TCTA family

Tissue Specificity

Ubiquitous. Highest level of expression in kidney. Present in monocytes, osteoclasts, macrophages, synoviocytes and synovial lining cells (at protein level).

Database Links

HGNC: 11692

OMIM: 600690

KEGG: hsa:6988

STRING: 9606.ENSP00000273590

UniGene: Hs.517962

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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