TFEC Antibody

Code CSB-PA023430GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TFEC
Alternative Names
bHLHe34 antibody; Class E basic helix-loop-helix protein 34 antibody; hTFEC-L antibody; TCFEC antibody; TFE-C antibody; Tfec antibody; TFEC protein antibody; TFEC_HUMAN antibody; TFECL antibody; Transcription factor EC antibody; Transcription factor EC-like antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TFEC
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
Gene References into Functions
  1. Two alternatively spliced TFEC isoforms have been found to be sequence-specific transcriptional activators of the nonmuscle myosin II heavy chain-A gene in transfected cells. PMID: 11467950
Subcellular Location
Nucleus.
Protein Families
MiT/TFE family
Tissue Specificity
Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
Database Links

HGNC: 11754

OMIM: 604732

KEGG: hsa:22797

STRING: 9606.ENSP00000265440

UniGene: Hs.125962

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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