THOC7 Antibody

Datasheet

Code	CSB-PA746911LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) THOC7 Polyclonal antibody

Uniprot No.

Q6I9Y2

Target Names

THOC7

Alternative Names

FLJ23445 antibody; fSAP24 antibody; Functional spliceosome associated protein 24 antibody; Functional spliceosome-associated protein 24 antibody; hTREX30 antibody; Ngg1 interacting factor 3 like 1 binding protein 1 antibody; Ngg1 interacting factor 3 like protein 1 binding protein 1 antibody; Ngg1-interacting factor 3-like protein 1-binding protein 1 antibody; NIF3L1 binding protein 1 antibody; NIF3L1-binding protein 1 antibody; NIF3L1BP1 antibody; THO complex 7 homolog (Drosophila) antibody; THO complex 7 homolog antibody; THO complex subunit 7 homolog antibody; THOC 7 antibody; thoc7 antibody; THOC7_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human THO complex subunit 7 homolog protein (4-204AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The THOC7 Antibody (Product code: CSB-PA746911LA01HU) is Non-conjugated. For THOC7 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA746911LB01HU	THOC7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA746911LC01HU	THOC7 Antibody, FITC conjugated
Biotin	CSB-PA746911LD01HU	THOC7 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.; The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

Gene References into Functions

THOC7 (50-137, amino acid numbers) binds to the N-terminal portion (1-199) of FMIP directly. PMID: 19059247

Subcellular Location

Cytoplasm. Nucleus. Nucleus speckle.

Protein Families

THOC7 family

Database Links

HGNC: 29874

OMIM: 611965

KEGG: hsa:80145

STRING: 9606.ENSP00000295899

UniGene: Hs.288151

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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