TMEM131L Antibody, HRP conjugated

Code CSB-PA012218NB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM131L Polyclonal antibody
Uniprot No.
Target Names
TMEM131L
Alternative Names
TMEM131L antibody; KIAA0922 antibody; Transmembrane protein 131-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Peptide sequence from Human Transmembrane protein 131-like protein (963-978AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation.
Gene References into Functions
  1. These results show that TMEM131L corresponds to an evolutionary conserved regulator of the Notch signaling pathway. PMID: 28347816
  2. these data indicate that, during thymopoiesis, stage-specific surface translocation of TMEM131L may regulate immature single-positive thymocyte proliferation arrest PMID: 23690469
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm.; [Isoform 1]: Endoplasmic reticulum.; [Isoform 5]: Cytoplasm.
Protein Families
TMEM131 family
Tissue Specificity
Expressed in thymocytes.
Database Links

HGNC: 29146

OMIM: 616243

KEGG: hsa:23240

STRING: 9606.ENSP00000386787

UniGene: Hs.732450

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