TMEM131L Antibody

Code CSB-PA012218NA01HU
Size US$166
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Image
  • Immunofluorescence staining of U251 cells with CSB-PA012218NA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM131L Polyclonal antibody
Uniprot No.
Target Names
TMEM131L
Alternative Names
TMEM131L antibody; KIAA0922 antibody; Transmembrane protein 131-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Peptide sequence from Human Transmembrane protein 131-like protein (963-978AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TMEM131L Antibody (Product code: CSB-PA012218NA01HU) is Non-conjugated. For TMEM131L Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA012218NB01HU TMEM131L Antibody, HRP conjugated ELISA
FITC CSB-PA012218NC01HU TMEM131L Antibody, FITC conjugated
Biotin CSB-PA012218ND01HU TMEM131L Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation.
Gene References into Functions
  1. These results show that TMEM131L corresponds to an evolutionary conserved regulator of the Notch signaling pathway. PMID: 28347816
  2. these data indicate that, during thymopoiesis, stage-specific surface translocation of TMEM131L may regulate immature single-positive thymocyte proliferation arrest PMID: 23690469
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm.; [Isoform 1]: Endoplasmic reticulum.; [Isoform 5]: Cytoplasm.
Protein Families
TMEM131 family
Tissue Specificity
Expressed in thymocytes.
Database Links

HGNC: 29146

OMIM: 616243

KEGG: hsa:23240

STRING: 9606.ENSP00000386787

UniGene: Hs.732450

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