TMEM231 Antibody

Datasheet
Code CSB-PA862028LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q9H6L2
Image
  • Immunofluorescence staining of MCF-7 cells with CSB-PA862028LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Immunogen Recombinant Human Transmembrane protein 231 protein (161-261AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IF; Recommended dilution: IF:1:50-1:200
Relevance Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Transmembrane protein 231, TMEM231
Immunogen Species Human
Research Area Cell Biology
Target Names TMEM231
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
Involvement in disease Joubert syndrome 20 (JBTS20); Meckel syndrome 11 (MKS11)
Subcellular Location Cell projection, cilium membrane, Multi-pass membrane protein
Protein Families TMEM231 family
Database Links

HGNC: 37234

OMIM: 614949

KEGG: hsa:79583

UniGene: Hs.156784

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