TMEM231 Antibody, FITC conjugated

Datasheet
Code CSB-PA862028LC01HU
Size US$299
Uniprot No. Q9H6L2
Protocols ELISA Protocol
Immunogen Recombinant Human Transmembrane protein 231 protein (161-261AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Transmembrane protein 231, TMEM231
Immunogen Species Homo sapiens (Human)
Research Area Cell Biology
Target Names TMEM231
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
Involvement in disease Joubert syndrome 20 (JBTS20); Meckel syndrome 11 (MKS11)
Subcellular Location Cell projection, cilium membrane, Multi-pass membrane protein
Protein Families TMEM231 family
Database Links

HGNC: 37234

OMIM: 614949

KEGG: hsa:79583

UniGene: Hs.156784

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