TMEM25 Antibody, Biotin conjugated

Code CSB-PA023821LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM25 Polyclonal antibody
Uniprot No.
Target Names
TMEM25
Alternative Names
0610039J01Rik antibody; FLJ14399 antibody; Tmem25 antibody; TMM25_HUMAN antibody; Transmembrane protein 25 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transmembrane protein 25 protein (27-322AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.
Gene References into Functions
  1. TMEM25 hypermethylation might play a significant role in altering expression of this gene in colorectal cancer. PMID: 23324576
  2. TMEM25 may be a useful tumor marker for favorable prognosis in breast cancer. PMID: 19776672
Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; Late endosome. Lysosome.
Tissue Specificity
Expressed throughout the brain with higher levels in the pyramidal cell layer of the hippocampal CA1 and CA3 regions. Also highly expressed iwhith the hippocampal dentate gyrus region and cerebellum and in scattered neurons in the cerebral cortex.
Database Links

HGNC: 25890

OMIM: 613934

KEGG: hsa:84866

UniGene: Hs.564188

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