TMEM9 Antibody

Code CSB-PA023894LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA023894LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA023894LA01HU at dilution of 1:100

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Description

CUSABIO generates the TMEM9 antibody by immunizing rabbits with the recombinant human TMEM9 (111-183AA). The resulting antibody is a polyclonal antibody and occurs as an unconjugated IgG. It is purified by protein G and reaches up to 95% in purity. And it is only reactive with human TMEM9 protein, which facilitates v-ATPase (vacuolar adenosine triphosphatase) assembly for vesicular acidification and lysosomal protein degradation. Studies have shown that TMEM9 hyperactivates Wnt signaling for liver regeneration and tumorigenesis through lysosomal degradation of APC. This TMEM9 antibody is suitable for the detection of the TMEM9 protein in ELISA and IHC analyses.

Full Product Name Rabbit anti-Homo sapiens (Human) TMEM9 Polyclonal antibody
Uniprot No. Q9P0T7
Target Names TMEM9
Alternative Names TMEM9 antibody; DERP4 antibody; TMEM9A antibody; HSPC186 antibody; PSEC0012 antibody; UNQ631/PRO1248 antibody; Transmembrane protein 9 antibody; Dermal papilla-derived protein 4 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Transmembrane protein 9 protein (111-183AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Earn $30 Amazon Card or 20μL/μg CUSABIO Trial Size Antibody. Details of rewards >>

Target Data

Function May be involved in intracellular transport.
Gene References into Functions
  1. TMEM9 plays a significant role in TNF-alpha-enhanced cytokines (IL-6 and IL-1beta) secretion in LX-2 cells and that the canonical Wnt/beta-catenin signaling pathway is involved in the induction of these cytokine expressions. PMID: 30119033
  2. TMEM9 knockdown by RNA interference resulted in G1 arrest. PMID: 27220462
  3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  4. phylogenetically conserved, widely expressed transmembrane protein with a potential, but unknown function in intracellular transport that localizes to lysosomes and late endosomes PMID: 12359240
  5. TMEM9B is a key component of inflammatory signaling pathways and suggest that endosomal or lysosomal compartments regulate these pathways PMID: 18541524

Show More

Hide All

Subcellular Location Late endosome membrane, Single-pass type I membrane protein, Lysosome membrane, Single-pass type I membrane protein
Protein Families TMEM9 family
Tissue Specificity Highly expressed in adrenal gland, thyroid gland, testis, ovary and prostate. Moderate expression in trachea, spinal cord, stomach, colon, small intestine and spleen. Low expression in bone marrow, lymph node, thymus and peripheral blood lymphocytes. Expr
Database Links

HGNC: 18823

OMIM: 616877

KEGG: hsa:252839

STRING: 9606.ENSP00000356298

UniGene: Hs.181444

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

© 2007-2021 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1